Chun-Shiang Chung Selected Research

Punctures

1/2022	Patho-Mechanisms for Hemorrhage/Sepsis-Induced Indirect Acute Respiratory Distress Syndrome: A Role for Lung TIE1 and Its Regulation by Neutrophils.
1/2022	Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival.
1/2021	A Peptide-Based Checkpoint Immunomodulator Alleviates Immune Dysfunction in Murine Polymicrobial Sepsis.
1/2020	SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model.
1/2019	A novel role for programmed cell death receptor ligand 2 in sepsis-induced hepatic dysfunction.
1/2019	Herpes Virus Entry Mediator (HVEM) Expression Promotes Inflammation/ Organ Injury in Response to Experimental Indirect-Acute Lung Injury.
1/2018	Group 2 Innate Lymphoid Cells (ILC2s) Are Key Mediators of the Inflammatory Response in Polymicrobial Sepsis.
1/2018	PAD4 Deficiency Leads to Decreased Organ Dysfunction and Improved Survival in a Dual Insult Model of Hemorrhagic Shock and Sepsis.
1/2017	Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model.
1/2016	Enhanced Innate Inflammation Induced by Anti-BTLA Antibody in Dual Insult Model of Hemorrhagic Shock/Sepsis.

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Chun-Shiang Chung Research Topics

Disease

47	Sepsis (Septicemia) 01/2022 - 01/2002
15	Hemorrhage 01/2020 - 12/2002
10	Inflammation (Inflammations) 01/2022 - 04/2003
10	Acute Lung Injury 01/2020 - 04/2003
10	Hemorrhagic Shock 11/2019 - 04/2004
9	Shock 01/2022 - 01/2003
9	Lung Injury 01/2022 - 07/2004
5	Infections 11/2019 - 11/2013
5	Critical Illness (Critically Ill) 01/2018 - 01/2008
4	Septic Shock (Toxic Shock Syndrome) 01/2018 - 04/2009
4	Pneumonia (Pneumonitis) 08/2011 - 04/2003
2	Coinfection 05/2021 - 03/2015
2	Body Weight (Weight, Body) 04/2008 - 10/2002
1	Pulmonary Edema 01/2021
1	Systemic candidiasis 01/2021
1	Persistent Infection 01/2020
1	Communicable Diseases (Infectious Diseases) 01/2020
1	Hypovolemia 11/2019
1	Liver Diseases (Liver Disease) 01/2019
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 11/2016
1	Peritonitis 03/2015
1	Gram-Negative Bacterial Infections 03/2015
1	Cross Infection (Nosocomial Infection) 11/2013
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2011
1	Multiple Organ Failure (MODS) 01/2008
1	Necrosis 01/2007
1	Traumatic Shock 06/2005

Drug/Important Bio-Agent (IBA)

15	Small Interfering RNA (siRNA)IBA 01/2020 - 01/2005
14	CytokinesIBA 01/2022 - 04/2004
13	Proteins (Proteins, Gene)FDA Link 01/2019 - 08/2005
7	Interleukin-6 (Interleukin 6)IBA 11/2019 - 12/2002
6	ChemokinesIBA 01/2022 - 04/2003
6	salicylhydroxamic acid (SHAM)IBA 01/2021 - 10/2002
6	LigandsIBA 01/2021 - 08/2011
6	Death Domain ReceptorsIBA 08/2013 - 10/2005
5	Peroxidase (Myeloperoxidase)IBA 01/2021 - 12/2002
5	Interleukin-10 (Interleukin 10)IBA 01/2018 - 01/2004
4	Peptides (Polypeptides)IBA 01/2021 - 08/2005
4	Biomarkers (Surrogate Marker)IBA 11/2016 - 04/2009
4	Caspase 3 (Caspase-3)IBA 01/2015 - 04/2010
4	Fas Ligand Protein (Fas Ligand)IBA 08/2011 - 01/2003
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2012 - 12/2005
3	CaspasesIBA 04/2010 - 01/2005
2	Immune Checkpoint ProteinsIBA 01/2022 - 01/2018
2	Immunologic Factors (Immunomodulators)IBA 01/2021 - 01/2020
2	Monoclonal AntibodiesIBA 01/2020 - 01/2016
2	Biological ProductsIBA 01/2018 - 07/2008
2	LipopolysaccharidesIBA 05/2007 - 04/2004
2	Caspase 8 (Caspase-8)IBA 12/2005 - 10/2005
2	InterleukinsIBA 12/2005 - 12/2002
2	Immunoglobulin G (IgG)IBA 08/2005 - 04/2003
1	Interleukin-33IBA 05/2021
1	Programmed Cell Death 1 ReceptorIBA 01/2021
1	chitotriosidaseIBA 01/2021
1	AntibodiesIBA 01/2021
1	chitobioseIBA 01/2021
1	phenylhydrazonopyrazolone sulfonate 1IBA 01/2020
1	Malaria VaccinesIBA 01/2020
1	Vaccine AdjuvantsIBA 01/2020
1	VaccinesIBA 01/2020
1	Ringer's LactateIBA 11/2019
1	Phosphates (Orthophosphate)IBA 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Immune Checkpoint InhibitorsIBA 01/2018
1	Tight Junction ProteinsIBA 01/2017
1	N- alpha- benzoyl- N5- (2- chloro- 1- iminoethyl)- L- ornithine amideIBA 01/2017
1	Histones (Histone)IBA 01/2017
1	IceIBA 01/2017
1	AB103IBA 03/2015
1	Trans-Activators (Trans-Acting Factor)IBA 01/2015
1	SNARE Proteins (SNAREs)IBA 01/2015
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2015
1	Coloring Agents (Dyes)IBA 11/2014
1	Glycoproteins (Glycoprotein)IBA 03/2013
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2013
1	Protein Kinases (Protein Kinase)IBA 11/2012
1	EndotoxinsIBA 11/2012
1	Complementary DNA (cDNA)IBA 11/2012
1	Type I Tumor Necrosis Factor ReceptorsIBA 08/2011
1	Caspase 9IBA 08/2010
1	BH3 Interacting Domain Death Agonist ProteinIBA 08/2010
1	Liposomes (Liposome)IBA 04/2009
1	Clodronic Acid (Clodronate)IBA 04/2009
1	Ethanol (Ethyl Alcohol)IBA 04/2008
1	SteroidsIBA 07/2007
1	PeptidomimeticsIBA 01/2007
1	Caspase InhibitorsIBA 01/2007
1	Interleukin-12 (IL 12)IBA 11/2006
1	eIF-2 Kinase (eIF 2 Kinase)IBA 12/2005
1	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2005
1	Interferon-alpha (Interferon Alfa)IBA 12/2005
1	Chemokine CXCL2IBA 08/2005
1	Carrier Proteins (Binding Protein)IBA 01/2005

Therapy/Procedure

37	Ligation 01/2022 - 01/2002
35	Punctures 01/2022 - 01/2002
4	Therapeutics 05/2021 - 05/2007
3	Resuscitation 11/2019 - 08/2005
1	Critical Care (Surgical Intensive Care) 05/2021
1	Length of Stay 11/2013
1	Intraperitoneal Injections 05/2007